Definition
• Post-exposure
prophylaxis (PEP) is any preventative medical therapy initiated immediately
after exposure to a pathogen (such as a disease-causing virus) in order to
avoid infection and disease progression.
Common post
exposure prophylaxis
HIV
• In the
instance of HIV exposure, post-exposure prophylaxis is a course of
antiretroviral medications that minimizes the likelihood of zero conversion
following high-risk HIV exposure episodes (e.g., unprotected anal or vaginal
sex, needle stick injuries, or needle sharing)
• PEP is
recommended by the CDC for any HIV-negative individual who has recently been
exposed to HIV for any reason.
• Treatment should begin within an hour of exposure for maximum effectiveness.
• PEP is
substantially less effective beyond 72 hours, and may not be useful at all.
Hepatitis B
• If the
individual exposed is an HBsAg positive source (a known responder to HBV
vaccination), then a booster dose should be administered if exposed to
hepatitis B.
• If they are
being vaccinated or are a non-responder, they must get hepatitis B immune
globulin (HBIG) and the vaccination.
• For HCV
post-exposure prophylaxis, neither immunoglobulin nor antiviral medications are
advised.
Rabies
• PEP is widely and very efficiently used to
prevent the spread of rabies following a rabid animal bite.
• The therapy
comprises of rabies vaccination and immunoglobulin injections given repeatedly.
Tetanus
• Tetanus
post-exposure treatment consists of two to three doses of tetanus vaccination
and immunoglobulin.
Prophylactic
immunization
• The artificial
induction of particular immunity, known as prophylactic vaccination, is a
technique that has dramatically decreased suffering and mortality from a number
of infectious illnesses.
There are two
types of prophylactic immunization:
1. Passive immunization, which confers protection
by injecting premade antibodies or lymphocytes from another person whose immune
system, has been triggered by the proper antigen.
2. Active immunization, in which protection is
obtained by administering a vaccine containing dead or harmless live forms of
an organism or an inactivated toxin, which encourages the immune system to
create lymphocytes and antibodies against that organism or toxin.
Passive Immunization
• An infectious
organism or a toxic chemical can sometimes have such a quick detrimental effect
that the recipient does not have time to build an immune response naturally.
• Passive
vaccination with premade antibodies can give life-saving support in battling
the disease or toxin at such times.
• This scenario
can occur in victims of toxic snakebites or botulism, as well as in people who
have advanced diseases such as diphtheria, tetanus, or gas gangrene to the
point where bacterial toxins have been absorbed into the circulation.
• It is also the
case with rabid animal bites, albeit active vaccination is started at the same
time since the progression of rabies infection to the central nervous system is
rather sluggish.
Active immunization
• Active immunization
seeks to guarantee that the body has a sufficient quantity of antibodies or T
and B cells that respond against a possible infectious agent or toxin before
infection or exposure to the toxin occurs.
• Once primed,
the immune system may either prevent the pathogen from establishing itself or
quickly mobilize the numerous defensive systems outlined above to stop the
infection or toxin in its early phases.
• Vaccines used
to deliver active immunization do not have to include alive germs.
Where to Get PEP - Safe
Hands Multispecialty STD Clinic is one of the well known STD Clinic in Delhi.
Here Dr. Vinod Raina HIV Specialist who has taken care of about 54k
patients in his 22 years of experienced career.
How do you reach Safe
Hands Multispecialty STD Clinic?
India's
famous Dr. Vinod Raina has been in the post of CMO in Delhi's Safdarjung
Hospital, he has been treating patients suffering from HIV for the last 22
years. You should get PEP treatment in Delhi
To
reach Dr. Vinod Raina, you can contact him on WhatsApp on his number
+91-9136363692. You can also contact him on his email address & our
official website:
https://www.pepforhivtreatment.com/
Call
us 9136363692, 9871605858
Watch our video -
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