Post exposure prophylaxis (PEP)

 Definition

• Post-exposure prophylaxis (PEP) is any preventative medical therapy initiated immediately after exposure to a pathogen (such as a disease-causing virus) in order to avoid infection and disease progression.

Common post exposure prophylaxis 

HIV

• In the instance of HIV exposure, post-exposure prophylaxis is a course of antiretroviral medications that minimizes the likelihood of  zero conversion following high-risk HIV exposure episodes (e.g., unprotected anal or vaginal sex, needle stick injuries, or needle sharing)

• PEP is recommended by the CDC for any HIV-negative individual who has recently been exposed to HIV for any reason.

• Treatment should begin within an hour of exposure for maximum effectiveness.

• PEP is substantially less effective beyond 72 hours, and may not be useful at all.

Hepatitis B

• If the individual exposed is an HBsAg positive source (a known responder to HBV vaccination), then a booster dose should be administered if exposed to hepatitis B.

• If they are being vaccinated or are a non-responder, they must get hepatitis B immune globulin (HBIG) and the vaccination.

Hepatitis C

• For HCV post-exposure prophylaxis, neither immunoglobulin nor antiviral medications are advised.

Rabies

 • PEP is widely and very efficiently used to prevent the spread of rabies following a rabid animal bite.

• The therapy comprises of rabies vaccination and immunoglobulin injections given repeatedly.

Tetanus

• Tetanus post-exposure treatment consists of two to three doses of tetanus vaccination and immunoglobulin.

Prophylactic immunization

• The artificial induction of particular immunity, known as prophylactic vaccination, is a technique that has dramatically decreased suffering and mortality from a number of infectious illnesses.

There are two types of prophylactic immunization:  

1.   Passive immunization, which confers protection by injecting premade antibodies or lymphocytes from another person whose immune system, has been triggered by the proper antigen.

2.  Active immunization, in which protection is obtained by administering a vaccine containing dead or harmless live forms of an organism or an inactivated toxin, which encourages the immune system to create lymphocytes and antibodies against that organism or toxin.

Passive Immunization

• An infectious organism or a toxic chemical can sometimes have such a quick detrimental effect that the recipient does not have time to build an immune response naturally.

• Passive vaccination with premade antibodies can give life-saving support in battling the disease or toxin at such times.

• This scenario can occur in victims of toxic snakebites or botulism, as well as in people who have advanced diseases such as diphtheria, tetanus, or gas gangrene to the point where bacterial toxins have been absorbed into the circulation.

• It is also the case with rabid animal bites, albeit active vaccination is started at the same time since the progression of rabies infection to the central nervous system is rather sluggish.

Active immunization

• Active immunization seeks to guarantee that the body has a sufficient quantity of antibodies or T and B cells that respond against a possible infectious agent or toxin before infection or exposure to the toxin occurs.

• Once primed, the immune system may either prevent the pathogen from establishing itself or quickly mobilize the numerous defensive systems outlined above to stop the infection or toxin in its early phases.

• Vaccines used to deliver active immunization do not have to include alive germs.

Where to Get PEP -  Safe Hands Multispecialty STD Clinic is one of the well known STD Clinic in Delhi. Here Dr. Vinod Raina HIV Specialist who has taken care of about 54k patients in his 22 years of experienced career.

How do you reach Safe Hands Multispecialty STD Clinic?

India's famous Dr. Vinod Raina has been in the post of CMO in Delhi's Safdarjung Hospital, he has been treating patients suffering from HIV for the last 22 years. You should get PEP treatment in Delhi

To reach Dr. Vinod Raina, you can contact him on WhatsApp on his number +91-9136363692. You can also contact him on his email address & our official website:

https://www.pepforhivtreatment.com/

Call us 9136363692, 9871605858

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